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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Hipp1  -  hippocampal weight 1

Mus musculus

Synonyms: Hipp1a
 
 
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High impact information on Hipp1

  • The total hippocampal activity of AChE was also greatly reduced (25-39%, P less than 0.01) during that period as a result of both the reduction in specific activity and a reduction in hippocampal weight of the treated animals [1].
  • The Hipp gene loci modulate neuron number in the dentate gyrus, collectively shifting the population up or down by as much as 200,000 cells [2].

References

  1. Early phenobarbital-induced alterations in hippocampal acetylcholinesterase activity and behavior. Kleinberger, N., Yanai, J. Brain Res. (1985) [Pubmed]
  2. Complex trait analysis of the hippocampus: mapping and biometric analysis of two novel gene loci with specific effects on hippocampal structure in mice. Lu, L., Airey, D.C., Williams, R.W. J. Neurosci. (2001) [Pubmed]
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