Gene Review:
Ache - acetylcholinesterase
Mus musculus
Synonyms:
AChE, Acetylcholinesterase
- Muscular dystrophy by merosin deficiency decreases acetylcholinesterase activity in thymus of Lama2dy mice. Nieto-Cerón, S., del Campo, L.F., Muñoz-Delgado, E., Vidal, C.J., Campoy, F.J. J. Neurochem. (2005)
- Respiratory survival mechanisms in acetylcholinesterase knockout mouse. Chatonnet, F., Boudinot, E., Chatonnet, A., Taysse, L., Daulon, S., Champagnat, J., Foutz, A.S. Eur. J. Neurosci. (2003)
- Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice. Li, B., Duysen, E.G., Volpicelli-Daley, L.A., Levey, A.I., Lockridge, O. Pharmacol. Biochem. Behav. (2003)
- Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. Duysen, E.G., Li, B., Xie, W., Schopfer, L.M., Anderson, R.S., Broomfield, C.A., Lockridge, O. J. Pharmacol. Exp. Ther. (2001)
- Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease. Sberna, G., Sáez-Valero, J., Li, Q.X., Czech, C., Beyreuther, K., Masters, C.L., McLean, C.A., Small, D.H. J. Neurochem. (1998)
- Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer's disease. Dong, H., Csernansky, C.A., Martin, M.V., Bertchume, A., Vallera, D., Csernansky, J.G. Psychopharmacology (Berl.) (2005)
- M2 muscarinic receptors in pontine reticular formation of C57BL/6J mouse contribute to rapid eye movement sleep generation. Coleman, C.G., Lydic, R., Baghdoyan, H.A. Neuroscience (2004)
- Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice. Capsoni, S., Giannotta, S., Stebel, M., Garcia, A.A., De Rosa, R., Villetti, G., Imbimbo, B.P., Pietra, C., Cattaneo, A. American journal of Alzheimer's disease and other dementias. (2004)
- Acute stress facilitates long-lasting changes in cholinergic gene expression. Kaufer, D., Friedman, A., Seidman, S., Soreq, H. Nature (1998)
- Association of the synaptic form of acetylcholinesterase with extracellular matrix in cultured mouse muscle cells. Inestrosa, N.C., Silberstein, L., Hall, Z.W. Cell (1982)
- Creatine kinase, myokinase, and acetylcholinesterase activities in muscle-forming primary cultures of mouse teratocarcinoma cells. Gearhart, J.D., Mintz, B. Cell (1975)
- Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes. Bonnefont, A.B., Muñoz, F.J., Inestrosa, N.C. FEBS Lett. (1998)
- Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase. Minic, J., Molgó, J., Karlsson, E., Krejci, E. Eur. J. Neurosci. (2002)
- Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon. Amitai, G., Moorad, D., Adani, R., Doctor, B.P. Biochem. Pharmacol. (1998)
- Inhibitory effects of huperzine B on cholinesterase activity in mice. Liu, J., Zhang, H.Y., Wang, L.M., Tang, X.C. Zhongguo yao li xue bao = Acta pharmacologica Sinica. (1999)
- Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent. Greig, N.H., Utsuki, T., Ingram, D.K., Wang, Y., Pepeu, G., Scali, C., Yu, Q.S., Mamczarz, J., Holloway, H.W., Giordano, T., Chen, D., Furukawa, K., Sambamurti, K., Brossi, A., Lahiri, D.K. Proc. Natl. Acad. Sci. U.S.A. (2005)
- CD41+/CD45+ cells without acetylcholinesterase activity are immature and a major megakaryocytic population in murine bone marrow. Matsumura-Takeda, K., Sogo, S., Isakari, Y., Harada, Y., Nishioka, K., Kawakami, T., Ono, T., Taki, T. Stem. Cells (2007)
- Promoter elements of the mouse acetylcholinesterase gene. Transcriptional regulation during muscle differentiation. Mutero, A., Camp, S., Taylor, P. J. Biol. Chem. (1995)
- Assignment of the gene for acetylcholinesterase to distal mouse chromosome 5. Rachinsky, T.L., Crenshaw, E.B., Taylor, P. Genomics (1992)
- Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models. Cousin, X., Strähle, U., Chatonnet, A. Bioessays (2005)
- The RNA-binding protein HuR binds to acetylcholinesterase transcripts and regulates their expression in differentiating skeletal muscle cells. Deschênes-Furry, J., Bélanger, G., Mwanjewe, J., Lunde, J.A., Parks, R.J., Perrone-Bizzozero, N., Jasmin, B.J. J. Biol. Chem. (2005)
- PRiMA: the membrane anchor of acetylcholinesterase in the brain. Perrier, A.L., Massoulié, J., Krejci, E. Neuron (2002)
- Reduced acetylcholinesterase (AChE) activity in adrenal medulla and loss of sympathetic preganglionic neurons in TrkA-deficient, but not TrkB-deficient, mice. Schober, A., Minichiello, L., Keller, M., Huber, K., Layer, P.G., Roig-López, J.L., García-Arrarás, J.E., Klein, R., Unsicker, K. J. Neurosci. (1997)
- Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine. Sowell, J.W., Tang, Y., Valli, M.J., Chapman, J.M., Usher, L.A., Vaughan, C.M., Kosh, J.W. J. Med. Chem. (1992)
- Butyrylcholinesterase and acetylcholinesterase activity and quantal transmitter release at normal and acetylcholinesterase knockout mouse neuromuscular junctions. Minic, J., Chatonnet, A., Krejci, E., Molgó, J. Br. J. Pharmacol. (2003)
- Non-cholinergic, trophic action of recombinant acetylcholinesterase on mid-brain dopaminergic neurons. Holmes, C., Jones, S.A., Budd, T.C., Greenfield, S.A. J. Neurosci. Res. (1997)
- The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane. Jacobson, C., Côté, P.D., Rossi, S.G., Rotundo, R.L., Carbonetto, S. J. Cell Biol. (2001)
- Postnatal maturation of brain cholinergic systems in the precocial murid Acomys cahirinus: comparison with the altricial rat. Pintor, A., Alleva, E., Michalek, H. Int. J. Dev. Neurosci. (1986)
- Effects of inhibitors of ornithine decarboxylase on the differentiation of mouse neuroblastoma cells. Chen, K.Y., Nau, D., Liu, A.Y. Cancer Res. (1983)
- The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase. Morton, C.L., Wadkins, R.M., Danks, M.K., Potter, P.M. Cancer Res. (1999)
- Oxidation of pesticides by purified cytochrome P-450 isozymes from mouse liver. Levi, P.E., Hodgson, E. Toxicol. Lett. (1985)
- A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme. Reyes, A.E., Perez, D.R., Alvarez, A., Garrido, J., Gentry, M.K., Doctor, B.P., Inestrosa, N.C. Biochem. Biophys. Res. Commun. (1997)
- Effect of depolarizing agents on choline acetyltransferase and acetylcholinesterase activities in primary cell cultures of spinal cord. Ishida, I., Deguchi, T. J. Neurosci. (1983)
- Accumulation of acetylcholine receptors is a necessary condition for normal accumulation of acetylcholinesterase during in vitro neuromuscular synaptogenesis. De La Porte, S., Chaubourt, E., Fabre, F., Poulas, K., Chapron, J., Eymard, B., Tzartos, S., Koenig, J. Eur. J. Neurosci. (1998)
- Expression of phenotypes in hybrid somatic cells derived from the nervous system. Minna, J.D., Yavelow, J., Coon, H.G. Genetics (1975)
- Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Birikh, K.R., Sklan, E.H., Shoham, S., Soreq, H. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Amyloid precursor protein fragment and acetylcholinesterase increase with cell confluence and differentiation in a neuronal cell line. Bronfman, F.C., Fernandez, H.L., Inestrosa, N.C. Exp. Cell Res. (1996)
- Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel. Luo, Z.D., Pincon-Raymond, M., Taylor, P. J. Neurochem. (1996)
- The readthrough variant of acetylcholinesterase remains very minor after heat shock, organophosphate inhibition and stress, in cell culture and in vivo. Perrier, N.A., Salani, M., Falasca, C., Bon, S., Augusti-Tocco, G., Massoulié, J. J. Neurochem. (2005)
- Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. Xie, W., Stribley, J.A., Chatonnet, A., Wilder, P.J., Rizzino, A., McComb, R.D., Taylor, P., Hinrichs, S.H., Lockridge, O. J. Pharmacol. Exp. Ther. (2000)