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Pacsin2  -  protein kinase C and casein kinase...

Rattus norvegicus

Synonyms: Protein kinase C and casein kinase substrate in neurons 2 protein, SdpII, Synaptic dynamin-associated protein II, Syndapin-2, Syndapin-II
 
 
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High impact information on Pacsin2

  • We here report the identification and characterization of SdpII, a ubiquitously expressed isoform of the brain-specific SdpI [1].
  • PACSIN 2 shows enhanced binding to the mSos proline-rich domain in pull-down assays from brain extracts as compared with lung extracts, suggesting a tissue-specific regulation of the interaction [2].

References

  1. Syndapin isoforms participate in receptor-mediated endocytosis and actin organization. Qualmann, B., Kelly, R.B. J. Cell Biol. (2000) [Pubmed]
  2. The Ras/Rac guanine nucleotide exchange factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin I, a regulator of endocytosis and the actin cytoskeleton. Wasiak, S., Quinn, C.C., Ritter, B., de Heuvel, E., Baranes, D., Plomann, M., McPherson, P.S. J. Biol. Chem. (2001) [Pubmed]
 
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