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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

pyrG  -  CTP synthase

Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

 
 
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High impact information on pyrG

  • Mutants devoid of CTP synthase activity require cytidine for growth and have been designated pyrG in an obligate cdd background [1].
  • CTP synthetase appeared to be repressed only when intracellular concentrations of uridine nucleotides were significantly lowered [2].

References

  1. Characterization of temperature-sensitive cytidine triphosphate synthase mutations in bacteria by high-performance liquid chromatography. Bailey, A.J., Dutta, P.K., Shanley, M.S., O'Donovan, G.A. J. Chromatogr. (1990) [Pubmed]
  2. Repression of cytidine triphosphate synthetase in Salmonella typhimurium by pyrimidines during uridine nucleotide depletion. West, T.P., O'Donovan, G.A. J. Gen. Microbiol. (1982) [Pubmed]
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