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Gene Review:

pol - RNA polymerase

Saccharomyces cerevisiae virus L-BC (La)

Fujimura, T. et al., Park, C.M. et al., Yao, W. et al., Wickner, R.B.

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High impact information on pol

Since the pol domain of the 180 kd minor coat protein appears to be responsible for the binding, this result suggests that the RNA polymerase molecule recognizes the viral genome for packaging [1].
20S RNA is an apparently naked circular RNA replicon (with a dsRNA form called W) encoding a RNA polymerase-like molecule [2].
The yeast virus ScV-L1 has only two genes, cap and pol, which encode the capsid polypeptide and the viral polymerase, respectively [3].

Biological context of pol

Both have two open reading frames on their single essential RNAs: cap (encoding a capsid polypeptide) and pol (encoding an RNA-dependent RNA polymerase) [4].

References

Portable encapsidation signal of the L-A double-stranded RNA virus of S. cerevisiae. Fujimura, T., Esteban, R., Esteban, L.M., Wickner, R.B. Cell (1990) [Pubmed]
Double-stranded and single-stranded RNA viruses of Saccharomyces cerevisiae. Wickner, R.B. Annu. Rev. Microbiol. (1992) [Pubmed]
Packaging in a yeast double-stranded RNA virus. Yao, W., Muqtadir, K., Bruenn, J.A. J. Virol. (1995) [Pubmed]
A second double-stranded RNA virus from yeast. Park, C.M., Lopinski, J.D., Masuda, J., Tzeng, T.H., Bruenn, J.A. Virology (1996) [Pubmed]

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