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High impact information on MYO3B
- Here we introduce a shorter class III myosin isoform, MYO3B, which is expressed in the retina, kidney, and testis [1].
- A product of 36 exons, MYO3B has several splice variants containing either one or two calmodulin binding (IQ) motifs in the neck domain and one of three predominant tail variations: a short tail ending just past the second IQ motif, or two alternatively spliced longer tails [1].
References
- A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome. Dosé, A.C., Burnside, B. Genomics (2002) [Pubmed]
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