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Gene Review

Nlgn3  -  neuroligin 3

Rattus norvegicus

Synonyms: Gliotactin homolog, Neuroligin-3
 
 
 
 
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High impact information on Nlgn3

  • A recent study reported that a mutation of neuroligin-3 (NL3), an X-linked gene, was found in siblings with autistic spectrum disorder in which two affected brothers had a point mutation that substituted a Cys for Arg451 [1].

References

  1. The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing. Comoletti, D., De Jaco, A., Jennings, L.L., Flynn, R.E., Gaietta, G., Tsigelny, I., Ellisman, M.H., Taylor, P. J. Neurosci. (2004) [Pubmed]
 
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