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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

rde-2  -  Protein RDE-2

Caenorhabditis elegans

 
 
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High impact information on rde-2

  • In contrast, the rde-2 and mut-7 genes were required downstream for interference [1].
  • Cosuppression is strongly abrogated in rde-2 and mut-7 mutants, but is not blocked in an rde-1 mutant, indicating that cosuppression and RNAi have overlapping but distinct genetic requirements [2].

References

  1. Genetic requirements for inheritance of RNAi in C. elegans. Grishok, A., Tabara, H., Mello, C.C. Science (2000) [Pubmed]
  2. Transgene-mediated cosuppression in the C. elegans germ line. Dernburg, A.F., Zalevsky, J., Colaiácovo, M.P., Villeneuve, A.M. Genes Dev. (2000) [Pubmed]
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