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Gene Review

bicA  -  bicarbonate transporter

Synechococcus sp. WH 8102

 
 
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Disease relevance of bicA

  • Through mutant studies in a coastal marine cyanobacterium, Synechococcus sp. strain PCC7002, we identified bicA as a gene that encodes a class of HCO(-)(3) transporter with relatively low transport affinity, but high flux rate [1].
 

High impact information on bicA

  • Further gain-of-function experiments in the freshwater cyanobacterium Synechococcus PCC7942 revealed that bicA expression alone is sufficient to confer a Na(+)-dependent, HCO(3)(-) uptake activity [1].

References

  1. Identification of a SulP-type bicarbonate transporter in marine cyanobacteria. Price, G.D., Woodger, F.J., Badger, M.R., Howitt, S.M., Tucker, L. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
 
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