Gene Review:
clec-15 - Protein CLEC-15
Caenorhabditis elegans
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Disease relevance of clec-15
- Here we show that that the intestinal GATA transcription factor ELT-2 is required for both immunity to Salmonella enterica and expression of a C-type lectin gene, clec-67, which is expressed in the intestinal cells and is a good marker of S. enterica infection [1].
References
- GATA Transcription Factor Required for Immunity to Bacterial and Fungal Pathogens. Kerry, S., Tekippe, M., Gaddis, N.C., Aballay, A. PLoS ONE (2006) [Pubmed]
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