Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

pry-1 - Protein PRY-1

Caenorhabditis elegans

Schmitz, C. et al., Gleason, J.E. et al.

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High impact information on pry-1

We show here that either mutation of pry-1 or expression of an activated BAR-1 beta-catenin protein causes an Overinduced phenotype, in which greater than three VPCs adopt induced cell fates [1].
In addition, we found axon guidance functions for known genes like pry-1, a component of the Wnt-signaling pathway, and ced-1, a receptor required for the engulfment of neurons undergoing apoptosis during development [2].

References

Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction. Gleason, J.E., Korswagen, H.C., Eisenmann, D.M. Genes Dev. (2002) [Pubmed]
Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Schmitz, C., Kinge, P., Hutter, H. Proc. Natl. Acad. Sci. U.S.A. (2007) [Pubmed]

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