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Gene Review

daf-5  -  Protein DAF-5

Caenorhabditis elegans

 
 
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High impact information on daf-5

  • We have studied the daf-5 gene, which, along with the daf-3 Smad gene, is antagonized by upstream receptors and receptor-regulated Smads [1].
  • Three other genes, daf-2, daf-3 and daf-5, displayed partial or complex epistasis interactions that were difficult to interpret as part of a simple linear pathway [2].

References

  1. DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGF beta pathway to regulate C. elegans dauer development. da Graca, L.S., Zimmerman, K.K., Mitchell, M.C., Kozhan-Gorodetska, M., Sekiewicz, K., Morales, Y., Patterson, G.I. Development (2004) [Pubmed]
  2. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Vowels, J.J., Thomas, J.H. Genetics (1992) [Pubmed]
 
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