Gene Review:
daf-2 - Protein DAF-2
Caenorhabditis elegans
- Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. Barsyte, D., Lovejoy, D.A., Lithgow, G.J. FASEB J. (2001)
- A defect in the activity of Delta6 and Delta5 desaturases may be a factor predisposing to the development of insulin resistance syndrome. Das, U.N. Prostaglandins Leukot. Essent. Fatty Acids (2005)
- Oxygen? No thanks, I'm on a diet. Longo, V.D. Science of aging knowledge environment [electronic resource] : SAGE KE (2002)
- Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Tissenbaum, H.A., Guarente, L. Nature (2001)
- Direct control of the Forkhead transcription factor AFX by protein kinase B. Kops, G.J., de Ruiter, N.D., De Vries-Smits, A.M., Powell, D.R., Bos, J.L., Burgering, B.M. Nature (1999)
- Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. Larsen, P.L., Clarke, C.F. Science (2002)
- daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Kimura, K.D., Tissenbaum, H.A., Liu, Y., Ruvkun, G. Science (1997)
- daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Lin, K., Dorman, J.B., Rodan, A., Kenyon, C. Science (1997)
- The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. Honda, Y., Honda, S. FASEB J. (1999)
- Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. McElwee, J.J., Schuster, E., Blanc, E., Thomas, J.H., Gems, D. J. Biol. Chem. (2004)
- Uncoupling of longevity and telomere length in C. elegans. Raices, M., Maruyama, H., Hugo, A., Karlseder, J. PLoS Genet. (2005)
- A systematic RNAi screen for longevity genes in C. elegans. Hamilton, B., Dong, Y., Shindo, M., Liu, W., Odell, I., Ruvkun, G., Lee, S.S. Genes Dev. (2005)
- Aging-dependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans. Murakami, H., Bessinger, K., Hellmann, J., Murakami, S. J. Neurosci. (2005)
- Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450. Mak, H.Y., Ruvkun, G. Development (2004)
- Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress. Lamitina, S.T., Strange, K. Am. J. Physiol., Cell Physiol. (2005)
- Both insulin and calcium channel signaling are required for developmental regulation of serotonin synthesis in the chemosensory ADF neurons of Caenorhabditis elegans. Estevez, A.O., Cowie, R.H., Gardner, K.L., Estevez, M. Dev. Biol. (2006)
- Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Wolkow, C.A., Kimura, K.D., Lee, M.S., Ruvkun, G. Science (2000)
- Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans. McElwee, J.J., Schuster, E., Blanc, E., Thornton, J., Gems, D. Mech. Ageing Dev. (2006)
- Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472]. McElwee, J.J., Schuster, E., Blanc, E., Thornton, J., Gems, D. Mech. Ageing Dev. (2006)
- HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans. Treinin, M., Shliar, J., Jiang, H., Powell-Coffman, J.A., Bromberg, Z., Horowitz, M. Physiol. Genomics (2003)
- The 14-3-3 protein FTT-2 regulates DAF-16 in Caenorhabditis elegans. Li, J., Tewari, M., Vidal, M., Sylvia Lee, S. Dev. Biol. (2007)
- Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans. Meissner, B., Boll, M., Daniel, H., Baumeister, R. J. Biol. Chem. (2004)
- The adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans. Hopper, N.A. Genetics (2006)
- Protein carbonyl accumulation in aging dauer formation-defective (daf) mutants of Caenorhabditis elegans. Yasuda, K., Adachi, H., Fujiwara, Y., Ishii, N. J. Gerontol. A Biol. Sci. Med. Sci. (1999)
- The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans. Murakami, S., Johnson, T.E. Curr. Biol. (2001)
- DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs. Yu, H., Larsen, P.L. J. Mol. Biol. (2001)
- Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Vowels, J.J., Thomas, J.H. Genetics (1992)
- Genes that regulate both development and longevity in Caenorhabditis elegans. Larsen, P.L., Albert, P.S., Riddle, D.L. Genetics (1995)
- A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Tatar, M., Kopelman, A., Epstein, D., Tu, M.P., Yin, C.M., Garofalo, R.S. Science (2001)