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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

eor-1  -  Protein EOR-1

Caenorhabditis elegans

 
 
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High impact information on eor-1

  • eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans [1].
  • The spectrum of identified mutations argues strongly for the specificity of the enhancer screen and for a close involvement of eor-1 and eor-2 in Ras signaling [2].
 

Biological context of eor-1

  • We identified and cloned the genes, eor-1 and eor-2, which are required to specify the fate of cell death in male HSNs [1].
 

Other interactions of eor-1

  • In addition, this screen identified multiple alleles of two newly identified genes, eor-1 and eor-2, that play a relatively weak role in vulval fate specification but positively regulate Ras signaling during excretory system development and P12 fate specification [2].

References

  1. eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans. Hoeppner, D.J., Spector, M.S., Ratliff, T.M., Kinchen, J.M., Granat, S., Lin, S.C., Bhusri, S.S., Conradt, B., Herman, M.A., Hengartner, M.O. Dev. Biol. (2004) [Pubmed]
  2. A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans. Rocheleau, C.E., Howard, R.M., Goldman, A.P., Volk, M.L., Girard, L.J., Sundaram, M.V. Genetics (2002) [Pubmed]
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