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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

fkh-2  -  Protein FKH-2

Caenorhabditis elegans

 
 
 
 
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High impact information on fkh-2

  • Conservation of the fkh-2/pes-1 genetic redundancy between C. elegans and the related species C. briggsae was demonstrated [1].
 

Biological context of fkh-2

  • Whereas a weak, transitory effect was observed upon disruption of just T14G12.4 (renamed fkh-2) gene function, simultaneous disruption of the activity of both fkh-2 and pes-1 resulted in a penetrant lethal phenotype [1].

References

  1. Evolutionary conservation of redundancy between a diverged pair of forkhead transcription factor homologues. Molin, L., Mounsey, A., Aslam, S., Bauer, P., Young, J., James, M., Sharma-Oates, A., Hope, I.A. Development (2000) [Pubmed]
 
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