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Gene Review

gpa-12  -  Protein GPA-12

Caenorhabditis elegans

 
 
 
 
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High impact information on gpa-12

  • RNA-mediated gene interference for CeRhoGEF and gpa-12 resulted in similar phenotypes such as embryonic lethality and sensory and locomotive defects in adults [1].
  • Expression of DsRed or GFP under the control of the promoter of CeRhoGEF or gpa-12 revealed an overlap of their expression patterns in ventral cord motor neurons and several neurons in the head [1].

References

  1. Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans. Yau, D.M., Yokoyama, N., Goshima, Y., Siddiqui, Z.K., Siddiqui, S.S., Kozasa, T. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
 
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