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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

daf-8  -  Protein DAF-8

Caenorhabditis elegans

 
 
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High impact information on daf-8

  • DAF-14 Smad has a highly unusual structure completely lacking the N-terminal domain found in all other Smad proteins known to date. daf-14 genetically interacts with daf-8, which encodes another Smad, and the interaction suggests partial functional redundancy between these two Smad proteins [1].
  • Among these are mutations in daf-8 and daf-19, genes for which only one mutation had been previously identified [2].

References

  1. Targets of TGF-beta signaling in Caenorhabditis elegans dauer formation. Inoue, T., Thomas, J.H. Dev. Biol. (2000) [Pubmed]
  2. A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans. Malone, E.A., Thomas, J.H. Genetics (1994) [Pubmed]
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