Gene Review:
bbs-8 - Protein BBS-8
Caenorhabditis elegans
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High impact information on bbs-8
- The BBS proteins BBS-7 and BBS-8 are required to stabilize complexes of IFT particles containing both of the IFT motors, because IFT particles in bbs-7 and bbs-8 mutants break down into two subcomplexes, IFT-A and IFT-B, which are moved separately by kinesin-II and OSM-3 kinesin, respectively [1].
References
- Functional coordination of intraflagellar transport motors. Ou, G., Blacque, O.E., Snow, J.J., Leroux, M.R., Scholey, J.M. Nature (2005) [Pubmed]
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