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Gene Review: 

EYCL3  -  eye color 3 (brown)

Homo sapiens

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High impact information on EYCL3

  • The P gene is located on chromosome 15q11.2-q12, which is also the location of a putative eye pigmentation gene (EYCL3) inferred to exist by linkage analysis [1].
  • The gene (DN10 or P) homologous to the pink-eye-dilution gene (p) in mice could be a candidate gene for BEY2 or for HCL3 [2].
  • Brown eye colour (BEY), or total brown iris pigmentation is one of the most common phenotypes of iris colour [2].

References

  1. P gene as an inherited biomarker of human eye color. Rebbeck, T.R., Kanetsky, P.A., Walker, A.H., Holmes, R., Halpern, A.C., Schuchter, L.M., Elder, D.E., Guerry, D. Cancer Epidemiol. Biomarkers Prev. (2002) [Pubmed]
  2. Assignment of genes coding for brown eye colour (BEY2) and brown hair colour (HCL3) on chromosome 15q. Eiberg, H., Mohr, J. Eur. J. Hum. Genet. (1996) [Pubmed]
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