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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SDK1  -  sidekick cell adhesion molecule 1

Homo sapiens

Synonyms: FLJ31425, Protein sidekick-1
 
 
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High impact information on SDK1

  • Exogenous addition of Sph or N,N-dimethyl-Sph to U937 cells causes caspase 3 activation and release of PKCdelta KD (SDK1), leading to apoptosis [1].
  • As the family was too small for genome-wide linkage, we considered several candidate loci, including the sidekick SDK1 and SDK2 genes [2].

References

  1. Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert. Suzuki, E., Handa, K., Toledo, M.S., Hakomori, S. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. Congenital stationary night blindness: report of an autosomal recessive family and linkage analysis. Abramowicz, M.J., Ribai, P., Cordonnier, M. Am. J. Med. Genet. A (2005) [Pubmed]
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