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Gene Review:

HSPA4L - heat shock 70kDa protein 4-like

Homo sapiens

Synonyms: APG-1, APG1, HSPH3, Heat shock 70 kDa protein 4L, Heat shock 70-related protein APG-1, ...

Fujita, J., Matsumori, M. et al.

Fujita,

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Disease relevance of HSPA4L

Although previous studies have mostly dealt with temperatures below 20 degrees C, mild hypothermia (32 degrees C) can change the cell's response to subsequent stresses as exemplified by APG-1, a member of the HSP110 family [1].

High impact information on HSPA4L

A partial amino-acid sequence (24 amino-acid residues) of the protein was determined and coincided with those of the mouse testis- and brain-specific APG-1 and osmotic stress protein 94 (OSP94) [2].

References

Cold shock response in mammalian cells. Fujita, J. J. Mol. Microbiol. Biotechnol. (1999) [Pubmed]
Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization. Matsumori, M., Itoh, H., Toyoshima, I., Komatsuda, A., Sawada, K., Fukuda, J., Tanaka, T., Okubo, A., Kinouchi, H., Mizoi, K., Hama, T., Suzuki, A., Hamada, F., Otaka, M., Shoji, Y., Takada, G. Eur. J. Biochem. (2002) [Pubmed]

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