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Gene Review

ANKRD26  -  ankyrin repeat domain 26

Homo sapiens

Synonyms: Ankyrin repeat domain-containing protein 26, KIAA1074, THC2, bA145E8.1
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High impact information on ANKRD26

  • The 13 POTE genes are dispersed among eight different chromosomes and evolved by duplications and remodeling of the human genome from an ancestral gene, ANKRD26 [1].
  • A comprehensive comparison of the genomic organization indicates that ANKRD26 has the genomic structure of the possible ancestor of ANKRD30A and all POTE family genes [2].


  1. Evolution and expression of chimeric POTE-actin genes in the human genome. Lee, Y., Ise, T., Ha, D., Saint Fleur, A., Hahn, Y., Liu, X.F., Nagata, S., Lee, B., Bera, T.K., Pastan, I. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  2. Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains. Hahn, Y., Bera, T.K., Pastan, I.H., Lee, B. Gene (2006) [Pubmed]
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