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Gene Review:

Pcyt1b - phosphate cytidylyltransferase 1, choline,...

Mus musculus

Synonyms: AW045697, CCT B, CCT-beta, CT B, CTP:phosphocholine cytidylyltransferase B, ...

Sugimoto, H. et al., Wang, L. et al.

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High impact information on Pcyt1b

Multiple CCT isoforms, CCTalpha, CCTbeta2, and CCTbeta3, are encoded by two genes, Pcyt1a and Pcyt1b [1].

Associations of Pcyt1b with chemical compounds

Phosphatidylcholine biosynthesis via the CDP-choline pathway is primarily regulated by CTP:phosphocholine cytidylyltransferase (CT) encoded by the Pcyt1a and Pcyt1b genes [2].

References

Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Wang, L., Magdaleno, S., Tabas, I., Jackowski, S. Mol. Cell. Biol. (2005) [Pubmed]
Sp1 is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP:phosphocholine cytidylyltransferase alpha. Sugimoto, H., Okamura, K., Sugimoto, S., Satou, M., Hattori, T., Vance, D.E., Izumi, T. J. Biol. Chem. (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PCYT1B	Bos taurus
PCYT1B	Canis lupus familiaris
pcyt1ba	Danio rerio
PCYT1B	Gallus gallus
PCYT1B	Homo sapiens
PCYT1B	Macaca mulatta
Os08g0161800	Oryza sativa Japonica Group
Os10g0578900	Oryza sativa Japonica Group
Pcyt1b	Rattus norvegicus
pcyt1b	Xenopus (Silurana) tropicalis

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