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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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About

Terms

 

Gene Review: 

Sgcz  -  sarcoglycan zeta

Mus musculus

Synonyms: C230085N17Rik, ZSG1, Zeta-SG, Zeta-sarcoglycan
 
 
 
 
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Disease relevance of Sgcz

 

High impact information on Sgcz

  • Additionally, zeta-sarcoglycan was reduced at the membrane in muscular dystrophy, consistent with a role in mediating membrane stability. zeta-Sarcoglycan was also found as a component of the vascular smooth muscle sarcoglycan complex [1].
  • We generated a zeta-sarcoglycan-specific antibody and found that zeta-sarcoglycan associated with other members of the sarcoglycan complex at the plasma membrane [1].

References

  1. Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Wheeler, M.T., Zarnegar, S., McNally, E.M. Hum. Mol. Genet. (2002) [Pubmed]
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