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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

sum3  -  ATP-dependent RNA helicase Sum3

Schizosaccharomyces pombe 972h-

 
 
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High impact information on sum3

  • The transcription factor thi1 and, surprisingly, the ATP-dependent RNA helicase ded1 were initially shown to enhance gene silencing in this system [1].
  • Disruption of the moc2 gene indicated that moc2 is essential for cell growth [2].
 

Biological context of sum3

  • The moc2 gene seems to have roles in both sexual differentiation and cell growth [2].

References

  1. Dominant genetic screen for cofactors that enhance antisense RNA-mediated gene silencing in fission yeast. Raponi, M., Arndt, G.M. Nucleic Acids Res. (2002) [Pubmed]
  2. Isolation of a novel gene, moc2, encoding a putative RNA helicase as a suppressor of sterile strains in Schizosaccharomyces pombe. Kawamukai, M. Biochim. Biophys. Acta (1999) [Pubmed]
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