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Gene Review

rpb10  -  DNA-directed RNA polymerase I, II, and III...

Schizosaccharomyces pombe 972h-

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Disease relevance of rpb10

  • Four subunits of Schizosaccharomyces pombe RNA polymerases I-III shared by all three enzymes (Rpb5, Rpb8, Rpb10 and Rpc10 [Rpb12]) have been overexpressed in Escherichia coli expression vectors pQE or pET as hexahistidine fusions [1].


  1. Heterologous overexpression and purification of four common subunits of nuclear RNA polymerases I, II and III of Schizosaccharomyces pombe. Proshkin, S.A., Shpakovski, G.V. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2004) [Pubmed]
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