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Gene Review

aps1  -  diadenosine 5',5'''-p1,p6-hexaphosphate...

Schizosaccharomyces pombe 972h-

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Disease relevance of SPAC13G6.14

  • The gene, designated aps1, has been cloned and the protein has been purified from Escherichia coli with a yield of 10 mg of Aps1/L of culture [1].

High impact information on SPAC13G6.14

  • Disruption of aps1 resulted in a 52% decrease in Ap(6)A hydrolase activity in vitro, no detectable change in the intracellular Ap(5)A concentration, and 3-fold increased intracellular concentrations of PP-Ins P(5) and [PP](x)-InsP(x) [2].


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