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HSPA12A  -  heat shock 70kDa protein 12A

Homo sapiens

Synonyms: FLJ13874, Heat shock 70 kDa protein 12A, KIAA0417
 
 
 
 
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High impact information on HSPA12A

  • Furthermore, we investigated the distribution of HSPA12A and HSPA12B transcripts across the human and nonhuman primate brain [1].
  • HSPA12A messenger ribonucleic acid was significantly reduced (p < .01; mean log2 optical density difference = -.84) across subjects with schizophrenia but not in the DLPFC of subjects with major depression or in monkeys chronically treated with haloperidol [1].
  • BACKGROUND: Deoxyribonucleic acid microarray analyses of dorsolateral prefrontal cortex (DLPFC) area 9 from 10 matched pairs of schizophrenic and control subjects revealed a consistent and significant decrease (p = .001; mean log2 signal difference = -.58) in transcript expression for a gene clone KIAA0417 [1].

References

  1. Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia. Pongrac, J.L., Middleton, F.A., Peng, L., Lewis, D.A., Levitt, P., Mirnics, K. Biol. Psychiatry (2004) [Pubmed]
 
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