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Gene Review

TOR1AIP1  -  torsin A interacting protein 1

Homo sapiens

Synonyms: FLJ13142, LAP1, LAP1B, Lamin-associated protein 1B, Torsin-1A-interacting protein 1
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High impact information on TOR1AIP1

  • The sequence homology between the predicted rat LAP1B and huLAP1B was found to be 73.6% [1].
  • The transmembrane (TM) domain (aa 346-368) is required for the localization of the nuclear and endoplasmic reticulum membrane and that the TM domain and the C-terminal half of the nucleoplasmic domain (aa 190-331) are sufficient for the proper localization of LAP1B [1].


  1. Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants. Kondo, Y., Kondoh, J., Hayashi, D., Ban, T., Takagi, M., Kamei, Y., Tsuji, L., Kim, J., Yoneda, Y. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
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