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Gene Review: 

GGT3P  -  gamma-glutamyltransferase 3 pseudogene

Homo sapiens

Synonyms: GGT 3, GGT3, Gamma-glutamyltransferase 3, Glutathione hydrolase 3
 
 
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Disease relevance of GGT3

  • With the exception of GGT-2 activity, the mean values of total GGT, GGT-1 isoenzyme and bile acids differed significantly between the cholestasis positive and negative groups [1].
 

High impact information on GGT3

  • The VpreB gene, encoding part of the surrogate light chain, the GGT2 gene and the BCRL4 pseudogene were also mapped within the lambda locus [2].
 

Other interactions of GGT3

  • In most samples two bands were demonstrated, one located between albumin and alpha1-globulin, called GGT 1, the other located in the alpha2-globulin region, GGT 2 [3].

References

  1. The relevance of some laboratory tests in the diagnosis of cholestasis and the differentiation between intra- and extrahepatic obstruction. Kruiswijk, T., Holtkamp, H.C., Diaz, D., Seidel, B., Szakaly, M. Clin. Chim. Acta (1981) [Pubmed]
  2. Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2. Frippiat, J.P., Williams, S.C., Tomlinson, I.M., Cook, G.P., Cherif, D., Le Paslier, D., Collins, J.E., Dunham, I., Winter, G., Lefranc, M.P. Hum. Mol. Genet. (1995) [Pubmed]
  3. A new procedure for the visualization of multiple forms of gamma-glutamyl transferase (GGT). Results in normals, patients receiving enzyme-inducing drugs and patients having liver parenchymal lesions. Kok, P.J., Seidel, B., Holtkamp, H.C., Huisman, J. Clin. Chim. Acta (1978) [Pubmed]
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