Gene Review:
GGT1 - gamma-glutamyltransferase 1
Homo sapiens
Synonyms:
CD224, D22S672, D22S732, GGT, GGT 1, ...
- Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase. Rajpert-De Meyts, E., Heisterkamp, N., Groffen, J. Proc. Natl. Acad. Sci. U.S.A. (1988)
- An alternatively processed mRNA specific for gamma-glutamyl transpeptidase in human tissues. Pawlak, A., Cohen, E.H., Octave, J.N., Schweickhardt, R., Wu, S.J., Bulle, F., Chikhi, N., Baik, J.H., Siegrist, S., Guellaën, G. J. Biol. Chem. (1990)
- Three-year increase of gamma-glutamyltransferase level and development of type 2 diabetes in middle-aged men and women: the D.E.S.I.R. cohort. Andr??, P., Balkau, B., Born, C., Charles, M.A., Eschw??ge, E. Diabetologia (2006)
- Plasma membrane gamma-glutamyltransferase activity facilitates the uptake of vitamin C in melanoma cells. Corti, A., Raggi, C., Franzini, M., Paolicchi, A., Pompella, A., Casini, A.F. Free Radic. Biol. Med. (2004)
- Glucose intolerance and serum aminotransferase activities in Japanese men. Miyake, Y., Eguchi, H., Shinchi, K., Oda, T., Sasazuki, S., Kono, S. J. Hepatol. (2003)
- Erythrocytes as targets for gamma-glutamyltranspeptidase initiated pro-oxidant reaction. Aberkane, H., Stoltz, J.F., Galteau, M.M., Wellman, M. Eur. J. Haematol. (2002)
- The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase. Lawlor, D.A., Sattar, N., Smith, G.D., Ebrahim, S. Am. J. Epidemiol. (2005)
- Use of serum carbohydrate-deficient transferrin values to exclude alcoholic hepatitis from non-alcoholic steatohepatitis: a pilot study. Ohtsuka, T., Tsutsumi, M., Fukumura, A., Tsuchishima, M., Takase, S. Alcohol. Clin. Exp. Res. (2005)
- Individual differences in plasma ALT, AST and GGT: contributions of genetic and environmental factors, including alcohol consumption. Whitfield, J.B., Martin, N.G. Enzyme (1985)
- Naltrexone and disulfiram in patients with alcohol dependence and comorbid post-traumatic stress disorder. Petrakis, I.L., Poling, J., Levinson, C., Nich, C., Carroll, K., Ralevski, E., Rounsaville, B. Biol. Psychiatry (2006)
- Idiopathic biliary ductopenia in adults without symptoms of liver disease. Moreno, A., Carreño, V., Cano, A., González, C. N. Engl. J. Med. (1997)
- A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. Markowitz, M., Saag, M., Powderly, W.G., Hurley, A.M., Hsu, A., Valdes, J.M., Henry, D., Sattler, F., La Marca, A., Leonard, J.M. N. Engl. J. Med. (1995)
- Mutation in the gene encoding the stimulatory G protein of adenylate cyclase in Albright's hereditary osteodystrophy. Patten, J.L., Johns, D.R., Valle, D., Eil, C., Gruppuso, P.A., Steele, G., Smallwood, P.M., Levine, M.A. N. Engl. J. Med. (1990)
- Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification. Lüdecke, H.J., Senger, G., Claussen, U., Horsthemke, B. Nature (1989)
- Glutathione-dependent bioactivation of haloalkenes. Anders, M.W., Dekant, W. Annu. Rev. Pharmacol. Toxicol. (1998)
- Liver enzymes, the metabolic syndrome, and incident diabetes: the Mexico City diabetes study. Nannipieri, M., Gonzales, C., Baldi, S., Posadas, R., Williams, K., Haffner, S.M., Stern, M.P., Ferrannini, E. Diabetes Care (2005)
- Effects of moderate alcohol intake in fixed or variable amounts on concentration of serum lipids and liver enzymes in healthy young men. Frimpong, N.A., Lapp, J.A. Am. J. Clin. Nutr. (1989)
- Serum gamma-glutamyl transpeptidase is a determinant of insulin resistance independently of adiposity in Pima Indian children. Ortega, E., Koska, J., Salbe, A.D., Tataranni, P.A., Bunt, J.C. J. Clin. Endocrinol. Metab. (2006)
- Evidence for a substantial genetic influence on biochemical liver function tests: results from a population-based Danish twin study. Bathum, L., Petersen, H.C., Rosholm, J.U., Hyltoft Petersen, P., Vaupel, J., Christensen, K. Clin. Chem. (2001)
- Changes in serum enzymes in moderate drinkers after an alcohol challenge. Nemesánszky, E., Lott, J.A., Arato, M. Clin. Chem. (1988)
- Expression of multiple gamma-glutamyltransferase genes in man. Courtay, C., Heisterkamp, N., Siest, G., Groffen, J. Biochem. J. (1994)
- Gamma-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes. Nichols, T.C., Guthridge, J.M., Karp, D.R., Molina, H., Fletcher, D.R., Holers, V.M. Eur. J. Immunol. (1998)
- Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues. Courtay, C., Oster, T., Michelet, F., Visvikis, A., Diederich, M., Wellman, M., Siest, G. Biochem. Pharmacol. (1992)
- Gamma-glutamyl transpeptidase activity mediates NF-kappaB activation through lipid peroxidation in human leukemia U937 cells. Djavaheri-Mergny, M., Accaoui, M.J., Rouillard, D., Wietzerbin, J. Mol. Cell. Biochem. (2002)
- Oxidative status in patients with alcohol dependence: a clinical study in Taiwan. Peng, F.C., Tang, S.H., Huang, M.C., Chen, C.C., Kuo, T.L., Yin, S.J. J. Toxicol. Environ. Health Part A (2005)
- gamma-Glutamyltransferase isoenzyme pattern in workers exposed to tetrachloroethylene. Gennari, P., Naldi, M., Motta, R., Nucci, M.C., Giacomini, C., Violante, F.S., Raffi, G.B. Am. J. Ind. Med. (1992)
- Serum gamma-glutamyltransferase isoform complexed to LDL in the diagnosis of small hepatocellular carcinoma. Castaldo, G., Intrieri, M., Castellano, L., de Sio, I., Del Vecchio Blanco, C., Sacchetti, L., Salvatore, F. Clin. Chem. (1999)
- Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway. Pankiv, S., Møller, S., Bjørkøy, G., Moens, U., Huseby, N.E. Biochim. Biophys. Acta (2006)
- Elevation of gamma-glutamyltransferase activity in 293 HEK cells constitutively expressing antisense glutaminase mRNA. Wong, K.T., Lee, Y.Y., Brusic, V., Tan, J., Yap, M.G., Nissom, P.M. Metab. Eng. (2005)
- A new procedure for the visualization of multiple forms of gamma-glutamyl transferase (GGT). Results in normals, patients receiving enzyme-inducing drugs and patients having liver parenchymal lesions. Kok, P.J., Seidel, B., Holtkamp, H.C., Huisman, J. Clin. Chim. Acta (1978)
- Pharmacokinetics of an antisense phosphorothioate oligodeoxynucleotide against rev from human immunodeficiency virus type 1 in the adult male rat following single injections and continuous infusion. Iversen, P.L., Mata, J., Tracewell, W.G., Zon, G. Antisense Res. Dev. (1994)
- The 5' untranslated region of the human gamma-glutamyl transferase mRNA contains a tissue-specific active translational enhancer. Diederich, M., Wellman, M., Visvikis, A., Puga, A., Siest, G. FEBS Lett. (1993)
- Intramolecular crosslinking of monomeric fibrinogen by tissue transglutaminase. Murthy, S.N., Wilson, J., Guy, S.L., Lorand, L. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Localization of a gamma-glutamyl-transferase-related gene family on chromosome 22. Morris, C., Courtay, C., Geurts van Kessel, A., ten Hoeve, J., Heisterkamp, N., Groffen, J. Hum. Genet. (1993)
- The analysis of gamma-glutamyl transpeptidase gene in different type liver tissues. Han, G.Q., Qin, C.Y., Shu, R.H. World J. Gastroenterol. (2003)
- Human chronic fascioliasis: a possible cause of unexplained abnormal liver tests. Hussein, N.G., Mahmoud, M.M., Elsayad, M.H., Abdel-Tawab, S.M. Br. J. Biomed. Sci. (2004)
- Clinical laboratory manifestations of exposure to dioxin in children. A six-year study of the effects of an environmental disaster near Seveso, Italy. Mocarelli, P., Marocchi, A., Brambilla, P., Gerthoux, P., Young, D.S., Mantel, N. JAMA (1986)