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Gene Review

TRUB2  -  TruB pseudouridine (psi) synthase family...

Homo sapiens

Synonyms: CLONE24922
 
 
 
 
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High impact information on TRUB2

  • The TRUB1 and TRUB2 products could be the hitherto unidentified human tRNA psi synthases [1].
  • Phylogenetic analysis of the TruB domain revealed another human gene (approved symbol TRUB2) encoding a conserved TruB domain, located on human chromosome 9 [1].
 

Other interactions of TRUB2

  • Thus, the human TruB family includes at least three members: i.e. DKC1 (previously identified), TRUB1 and TRUB2 [1].

References

  1. The human TruB family of pseudouridine synthase genes, including the Dyskeratosis Congenita 1 gene and the novel member TRUB1. Zucchini, C., Strippoli, P., Biolchi, A., Solmi, R., Lenzi, L., D'Addabbo, P., Carinci, P., Valvassori, L. Int. J. Mol. Med. (2003) [Pubmed]
 
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