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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

mtd  -  major tropism determinant; Mtd

Bordetella phage BPP-1

 
 
 
 
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High impact information on mtd

  • Tropism switching results from the introduction of single nucleotide substitutions at defined locations in the VR1 (variable region 1) segment of the mtd (major tropism determinant) gene, which determines specificity for receptors on host bacteria [1].

References

  1. Genomic and genetic analysis of Bordetella bacteriophages encoding reverse transcriptase-mediated tropism-switching cassettes. Liu, M., Gingery, M., Doulatov, S.R., Liu, Y., Hodes, A., Baker, S., Davis, P., Simmonds, M., Churcher, C., Mungall, K., Quail, M.A., Preston, A., Harvill, E.T., Maskell, D.J., Eiserling, F.A., Parkhill, J., Miller, J.F. J. Bacteriol. (2004) [Pubmed]
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