Gene Review:
CNTN6 - contactin 6
Homo sapiens
Synonyms:
Contactin-6, NB-3, Neural recognition molecule NB-3, hNB-3
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High impact information on CNTN6
- It shares with rat NB-3 86% identity in nucleotide sequences and 90% identity in amino acid sequences [1].
- The cDNA clone, hNB-3, consists of 3,530 nucleotides with an open reading frame of 3,084 nucleotides encoding 1,028 amino acids [1].
Analytical, diagnostic and therapeutic context of CNTN6
- Northern blot analysis of mRNA isolated from different regions of the adult human nervous system showed that the hNB-3 mRNA content was regionally different by dozens-fold, although the mRNA was detected in all regions, as a transcript of 3.7 kb [1].
- Chromosomal localization of hNB-3, using fluorescence in situ hybridization, was assigned to 3p25-26 [1].
References
- cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human. Kamei, Y., Tsutsumi, O., Taketani, Y., Watanabe, K. J. Neurosci. Res. (1998) [Pubmed]
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