Gene Review:
gadY - ncRNA
Escherichia coli str. K-12 substr. MG1655
Synonyms:
ECK3500, IS183, JWR0255
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Disease relevance of gadY
- A previous bioinformatics-based search for small RNAs in Escherichia coli identified a novel RNA named IS183 [1].
High impact information on gadY
- A promoter mutation which abolished gadY expression resulted in a reduction in the amount of gadX mRNA during stationary phase [1].
- Given that IS183 is encoded in the gad gene cluster and because of its role in regulating acid response genes reported here, this RNA has been renamed GadY [1].
References
- GadY, a small-RNA regulator of acid response genes in Escherichia coli. Opdyke, J.A., Kang, J.G., Storz, G. J. Bacteriol. (2004) [Pubmed]
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