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Gene Review

TMED10P1  -  transmembrane emp24-like trafficking...

Homo sapiens

Synonyms: TMED10P, Tmp21-II
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High impact information on TMED10P

  • We further show the cloning and characterization of the human homologs, hum-Tmp21, which is expressed in two variants (Tmp21-I and Tmp21-II), and hum-p24A [1].
  • We conclude that Tmp21-II cDNA derives from a neutral pseudogene, which originates from a duplication event of the human Tmp21-isoform-I [2].


  1. Tmp21 and p24A, two type I proteins enriched in pancreatic microsomal membranes, are members of a protein family involved in vesicular trafficking. Blum, R., Feick, P., Puype, M., Vandekerckhove, J., Klengel, R., Nastainczyk, W., Schulz, I. J. Biol. Chem. (1996) [Pubmed]
  2. A comparative study of rat and human Tmp21 (p23) reveals the pseudogene-like features of human Tmp21-II. Hörer, J., Blum, R., Feick, P., Nastainczyk, W., Schulz, I. DNA Seq. (1999) [Pubmed]
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