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Gene Review:

areR - sigma(54)-dependent transcriptionnal...

Acinetobacter sp. ADP1

Jones, R.M. et al., Jones, R.M. et al.

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Disease relevance of areR

The areR gene in Acinetobacter sp. strain ADP1 regulates the expression of the areCBA genes, which determine growth on benzyl alkanoates [1].

High impact information on areR

Inactivation of areR and rpoN (for RNA polymerase sigma(54)) drastically reduced growth rates on the Are substrates and induction of the operon [2].
The areCBA genes in Acinetobacter sp. strain ADP1, determining growth on benzyl alkanoates, are shown to be transcribed as a single operon and regulated by areR, which encodes a regulatory protein of the NtrC/XylR family [2].

References

Mutational analysis of the critical bases involved in activation of the AreR-regulated sigma54-dependent promoter in Acinetobacter sp. strain ADP1. Jones, R.M., Williams, P.A. Appl. Environ. Microbiol. (2003) [Pubmed]
areCBA is an operon in Acinetobacter sp. strain ADP1 and Is controlled by AreR, a sigma(54)-dependent regulator. Jones, R.M., Williams, P.A. J. Bacteriol. (2001) [Pubmed]

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