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Gene Review

areR  -  sigma(54)-dependent transcriptionnal...

Acinetobacter sp. ADP1

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Disease relevance of areR

  • The areR gene in Acinetobacter sp. strain ADP1 regulates the expression of the areCBA genes, which determine growth on benzyl alkanoates [1].

High impact information on areR

  • Inactivation of areR and rpoN (for RNA polymerase sigma(54)) drastically reduced growth rates on the Are substrates and induction of the operon [2].
  • The areCBA genes in Acinetobacter sp. strain ADP1, determining growth on benzyl alkanoates, are shown to be transcribed as a single operon and regulated by areR, which encodes a regulatory protein of the NtrC/XylR family [2].


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