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Gene Review:

IGLJ6 - immunoglobulin lambda joining 6

Homo sapiens

Poul, M.A. et al., Tümkaya, T. et al.

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Disease relevance of IGLJ6

In case of precursor B-ALL we recommend including the IGLJ6 probe for the detection of rearrangements to J-Clambda6 [1].

High impact information on IGLJ6

The IGLJ6 joining segment as a STS in the human immunoglobulin lambda light chain constant region gene locus (located at 22q11) [2].

References

Immunoglobulin lambda isotype gene rearrangements in B cell malignancies. Tümkaya, T., van der Burg, M., Garcia Sanz, R., Gonzalez Diaz, M., Langerak, A.W., San Miguel, J.F., van Dongen, J.J. Leukemia (2001) [Pubmed]
The IGLJ6 joining segment as a STS in the human immunoglobulin lambda light chain constant region gene locus (located at 22q11). Poul, M.A., Zhang, X.M., Ducret, F., Lefranc, M.P. Nucleic Acids Res. (1991) [Pubmed]

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