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Gene Review

bclA  -  benzoate-CoA ligase

Aromatoleum aromaticum EbN1

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Disease relevance of bclA

  • Benzoate-CoA ligase assays and transcriptional analyses based on lacZ-reporter fusions revealed that benzoate degradation in Azoarcus sp. strain CIB is subject to carbon catabolite repression by some organic acids, indicating the existence of a physiological control that connects the expression of the bzd genes to the metabolic status of the cell [1].

Associations of bclA with chemical compounds


  1. The bzd gene cluster, coding for anaerobic benzoate catabolism, in Azoarcus sp. strain CIB. López Barragán, M.J., Carmona, M., Zamarro, M.T., Thiele, B., Boll, M., Fuchs, G., García, J.L., Díaz, E. J. Bacteriol. (2004) [Pubmed]
  2. Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii. Mohamed, M.E., Zaar, A., Ebenau-Jehle, C., Fuchs, G. J. Bacteriol. (2001) [Pubmed]
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