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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PhKgamma  -  Phosphorylase kinase gamma

Drosophila melanogaster

Synonyms: CG1830, DPhK-gamma, Dmel\CG1830, EP779, ESTS:194B3T, ...
 
 
 
 
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High impact information on PhKgamma

  • The amino acid sequence of DPhK-gamma is homologous to that of mammalian PhK-gamma proteins but differs in the length and amino acid composition of its linker sequence [1].
  • The predicted amino acid sequence of DPhK-gamma has two conserved domains, the catalytic kinase and calmodulin-binding domains, separated by a linker sequence [1].
  • DPhK-gamma is required in early embryonic processes, such as gastrulation and mesoderm formation; however, defects in these processes are seen only when both the maternal and zygotic components of DPhK-gamma expression are eliminated [1].

References

  1. DPhK-gamma, a putative Drosophila kinase with homology to vertebrate phosphorylase kinase gamma subunits: molecular characterisation of the gene and phenotypic analysis of loss of function mutants. Bahri, S.M., Chia, W. Mol. Gen. Genet. (1994) [Pubmed]
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