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Gene Review

ilvH  -  acetolactate synthase 3 regulatory subunit

Corynebacterium glutamicum ATCC 13032

 
 
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High impact information on ilvN

  • As in other bacteria, the AHAS of this gram-positive organism is encoded by two genes, ilvB and ilvN [1].
 

Analytical, diagnostic and therapeutic context of ilvN

  • By using site-directed mutagenesis, one to three amino acid alterations (mutations M8, M11, and M13) were introduced into the small (regulatory) AHAS subunit encoded by ilvN [2].

References

  1. Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon. Keilhauer, C., Eggeling, L., Sahm, H. J. Bacteriol. (1993) [Pubmed]
  2. Feedback-resistant acetohydroxy acid synthase increases valine production in Corynebacterium glutamicum. Elisáková, V., Pátek, M., Holátko, J., Nesvera, J., Leyval, D., Goergen, J.L., Delaunay, S. Appl. Environ. Microbiol. (2005) [Pubmed]
 
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