MeSH Review:
Mutagenesis, Site-Directed
- Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function. Malim, M.H., Böhnlein, S., Hauber, J., Cullen, B.R. Cell (1989)
- Crystallographic analysis of mutant human haemoglobins made in Escherichia coli. Luisi, B.F., Nagai, K. Nature (1986)
- Truncation of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Rhodospirillum rubrum affects the holoenzyme assembly and activity. Ranty, B., Lundqvist, T., Schneider, G., Madden, M., Howard, R., Lorimer, G. EMBO J. (1990)
- Effects of mutations in three domains of the vesicular stomatitis viral glycoprotein on its lateral diffusion in the plasma membrane. Scullion, B.F., Hou, Y., Puddington, L., Rose, J.K., Jacobson, K. J. Cell Biol. (1987)
- VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes. Guyader, M., Emerman, M., Montagnier, L., Peden, K. EMBO J. (1989)
- Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity. Xu, L.Z., Harrison, R.W., Weber, I.T., Pilkis, S.J. J. Biol. Chem. (1995)
- Genetic and structural evidence for antigen selection of anti-DNA antibodies. Radic, M.Z., Weigert, M. Annu. Rev. Immunol. (1994)
- Pharmacology of CFTR chloride channel activity. Schultz, B.D., Singh, A.K., Devor, D.C., Bridges, R.J. Physiol. Rev. (1999)
- The Drosophila nuclear receptor e75 contains heme and is gas responsive. Reinking, J., Lam, M.M., Pardee, K., Sampson, H.M., Liu, S., Yang, P., Williams, S., White, W., Lajoie, G., Edwards, A., Krause, H.M. Cell (2005)
- Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase. Zhang, X., Tamaru, H., Khan, S.I., Horton, J.R., Keefe, L.J., Selker, E.U., Cheng, X. Cell (2002)
- Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Hall, T.M., Porter, J.A., Young, K.E., Koonin, E.V., Beachy, P.A., Leahy, D.J. Cell (1997)
- Production of thiol-penicillin-binding protein 3 of Escherichia coli using a two primer method of site-directed mutagenesis. Broome-Smith, J.K., Hedge, P.J., Spratt, B.G. EMBO J. (1985)
- The oligomeric structure of nucleoid protein H-NS is necessary for recognition of intrinsically curved DNA and for DNA bending. Spurio, R., Falconi, M., Brandi, A., Pon, C.L., Gualerzi, C.O. EMBO J. (1997)
- Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles. Steinhauer, D.A., Wharton, S.A., Skehel, J.J., Wiley, D.C., Hay, A.J. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Electron transfer in a genetically modified bacterial reaction center containing a heterodimer. Kirmaier, C., Holten, D., Bylina, E.J., Youvan, D.C. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Site-directed mutagenesis identifies a tyrosine radical involved in the photosynthetic oxygen-evolving system. Debus, R.J., Barry, B.A., Babcock, G.T., McIntosh, L. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Mutagenesis of Fujinami sarcoma virus: evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activity. Weinmaster, G., Zoller, M.J., Smith, M., Hinze, E., Pawson, T. Cell (1984)
- Idealization of the hydrophobic segment of the alkaline phosphatase signal peptide. Kendall, D.A., Bock, S.C., Kaiser, E.T. Nature (1986)
- Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers. Berberich, S.J., Cole, M.D. Genes Dev. (1992)
- Functional comparison of the nematode Hox gene lin-39 in C. elegans and P. pacificus reveals evolutionary conservation of protein function despite divergence of primary sequences. Grandien, K., Sommer, R.J. Genes Dev. (2001)
- The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis. Tanner, N.K., Cordin, O., Banroques, J., Doère, M., Linder, P. Mol. Cell (2003)
- Localization of the binding site for the human high-affinity Fc receptor on IgG. Duncan, A.R., Woof, J.M., Partridge, L.J., Burton, D.R., Winter, G. Nature (1988)
- The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor. Morley, B.J., Chin, K.N., Newton, M.E., Weiss, A. J. Exp. Med. (1988)
- Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor. Choi, Y.B., Lipton, S.A. Neuron (1999)
- Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor. Fu, Y.K., Arkins, S., Fuh, G., Cunningham, B.C., Wells, J.A., Fong, S., Cronin, M.J., Dantzer, R., Kelley, K.W. J. Clin. Invest. (1992)
- CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission. Nardini, M., Spanò, S., Cericola, C., Pesce, A., Massaro, A., Millo, E., Luini, A., Corda, D., Bolognesi, M. EMBO J. (2003)
- The cdc25 protein contains an intrinsic phosphatase activity. Dunphy, W.G., Kumagai, A. Cell (1991)
- Structural requirements of a membrane-spanning domain for protein anchoring and cell surface transport. Adams, G.A., Rose, J.K. Cell (1985)
- Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Galzi, J.L., Devillers-Thiéry, A., Hussy, N., Bertrand, S., Changeux, J.P., Bertrand, D. Nature (1992)
- Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Jacks, T., Power, M.D., Masiarz, F.R., Luciw, P.A., Barr, P.J., Varmus, H.E. Nature (1988)
- Synthesis in yeast of a functional oxidation-resistant mutant of human alpha-antitrypsin. Rosenberg, S., Barr, P.J., Najarian, R.C., Hallewell, R.A. Nature (1984)
- The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression. Werner, M., Feller, A., Messenguy, F., Piérard, A. Cell (1987)
- A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. Schreuder, H., Tardif, C., Trump-Kallmeyer, S., Soffientini, A., Sarubbi, E., Akeson, A., Bowlin, T., Yanofsky, S., Barrett, R.W. Nature (1997)
- Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Sakahira, H., Enari, M., Nagata, S. Nature (1998)
- NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain. Huang, B., Eberstadt, M., Olejniczak, E.T., Meadows, R.P., Fesik, S.W. Nature (1996)
- Engineering human prolactin to bind to the human growth hormone receptor. Cunningham, B.C., Henner, D.J., Wells, J.A. Science (1990)
- Structure and function of receptors coupled to G proteins. Baldwin, J.M. Curr. Opin. Cell Biol. (1994)
- Escherichia coli aspartate transcarbamoylase: the molecular basis for a concerted allosteric transition. Kantrowitz, E.R., Lipscomb, W.N. Trends Biochem. Sci. (1990)
- Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit. Howitt, J.A., Clout, N.J., Hohenester, E. EMBO J. (2004)
- NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression. Krüger, M., Ruschke, K., Braun, T. EMBO J. (2004)
- Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae. TerBush, D.R., Novick, P. J. Cell Biol. (1995)