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Gene Review: 

AFUA_5G08890  -  homoaconitase LysF

Aspergillus fumigatus Af293

 
 
 
 
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High impact information on AFUA_5G08890

  • In order to determine the importance of lysine biosynthesis for growth and pathogenicity, the A. fumigatus lysF gene, encoding a homologue of the A. nidulans homoaconitase LysF, was cloned and characterized [1].

References

  1. Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis. Liebmann, B., Mühleisen, T.W., Müller, M., Hecht, M., Weidner, G., Braun, A., Brock, M., Brakhage, A.A. Arch. Microbiol. (2004) [Pubmed]
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