Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

subB - subtilase cytotoxin, subunit B

Escherichia coli

Patel, N.V. et al., Paton, A.W. et al.

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Disease relevance of subB

Oral challenge of mice with E. coli K-12-expressing cloned subA and subB resulted in dramatic weight loss [1].

High impact information on subB

Mapping of mRNA showed that each cytochrome P450-encoding gene was transcribed on a separate multicistronic mRNA that encodes cytochrome P-450 (suaC or subC), ferredoxin (suaB or subB) and at least one other open reading frame [2].

References

A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli. Paton, A.W., Srimanote, P., Talbot, U.M., Wang, H., Paton, J.C. J. Exp. Med. (2004) [Pubmed]
Phenobarbital and sulfonylurea-inducible operons encoding herbicide metabolizing cytochromes P-450 in Streptomyces griseolus. Patel, N.V., Omer, C.A. Gene (1992) [Pubmed]

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