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Gene Review

SOX1  -  SRY (sex determining region Y)-box 1

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High impact information on SOX1

  • This gene is a member of the subgroup B, which includes Sox1, Sox2 and Sox3 [1].
  • Semi-quantitative RT-PCE analysis of the expression of several transcription factors indicated that Sox1 and Sox3 were upregulated in parallel with delta1-crystallin mRNA in form-deprived eyes [2].


  1. cSox21 exhibits a complex and dynamic pattern of transcription during embryonic development of the chick central nervous system. Rex, M., Uwanogho, D.A., Orme, A., Scotting, P.J., Sharpe, P.T. Mech. Dev. (1997) [Pubmed]
  2. Up-regulation of crystallin mRNAs in form-deprived chick eyes. Ishibashi, K., Fujii, S., Escaño, M.F., Sekiya, Y., Yamamoto, M. Exp. Eye Res. (2000) [Pubmed]
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