Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

acp1-a - acid phosphatase 1, soluble

Xenopus laevis

Synonyms: LMW-PTP, XLPTP1, acp1, acp1a, haap, ...

Park, E.K. et al.

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High impact information on ptp1a-A

Finally, XLPTP1 physically associates only with an activated FGFR1, and this interaction requires the presence of SNT1/FRS-2 (FGFR substrate 2) [1].
Low-molecular-weight protein tyrosine phosphatase (LMW-PTP) has been implicated in the regulation of cell growth and actin rearrangement mediated by several receptor tyrosine kinases, including platelet-derived growth factor and epidermal growth factor [1].
Using morpholino antisense technology, we show that inhibition of endogenous XLPTP1 expression dramatically restricts anterior and posterior structure development and inhibits mesoderm formation [1].

References

Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway. Park, E.K., Warner, N., Mood, K., Pawson, T., Daar, I.O. Mol. Cell. Biol. (2002) [Pubmed]

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