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Gene Review:

glnR - glutamine synthetase repressor

Staphylococcus aureus RF122

Schreier, H.J. et al., Gustafson, J. et al.

Schreier, Caruso, Maier,

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Disease relevance of glnR

A GlnR homolog from Staphylococcus aureus was found to complement a B. subtilis glnR mutant, regulating GS levels and glnRA expression in a nitrogen-dependent manner [1].
Control of Bacillus subtilis glutamine synthetase expression by glnR from Staphylococcus aureus [1].

High impact information on glnR

Northern (RNA) blots probed with putative glnR or glnA fragments revealed that 1.7- and 1.9-kb transcripts characteristic of wild-type cells were replaced by less abundant 7.0- and 7.2-kb transcripts in the femC::omega 2005 mutant [2].

References

Control of Bacillus subtilis glutamine synthetase expression by glnR from Staphylococcus aureus. Schreier, H.J., Caruso, S.M., Maier, K.C. Curr. Microbiol. (2000) [Pubmed]
The femC locus of Staphylococcus aureus required for methicillin resistance includes the glutamine synthetase operon. Gustafson, J., Strässle, A., Hächler, H., Kayser, F.H., Berger-Bächi, B. J. Bacteriol. (1994) [Pubmed]

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