The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

LOC397753  -  Xcad 1

Xenopus laevis

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on LOC397753

  • Anterior-posterior patterning of the embryo requires the activity of multiple homeobox genes among them Hox, caudal (Cdx, Xcad) and Otx2 [1].
  • Xcad1 and Xcad2, two caudal-type homeobox genes, are expressed in a region with an anterior limit at this boundary and a posterior limit between the colon and proctodeum, therefore covering the whole of the small and large intestines [2].


  1. Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation in Xenopus. Tour, E., Pillemer, G., Gruenbaum, Y., Fainsod, A. Mech. Dev. (2002) [Pubmed]
  2. Regional gene expression in the epithelia of the Xenopus tadpole gut. Chalmers, A.D., Slack, J.M., Beck, C.W. Mech. Dev. (2000) [Pubmed]
WikiGenes - Universities