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Gene Review

egr1-a  -  early growth response 1

Xenopus laevis

Synonyms: EGR-1-A, Xegr-1, at225, egr, egr-1, ...
 
 
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High impact information on Egr1

  • Egr-1 is an immediate-early gene whose growth factor-stimulated transcriptional induction displays a transient activity profile and occurs independent of protein synthesis [1].
  • Transcription factors such as Msx-1, Msx-2 and Egr-1, growth factors, including TGF beta's, BMPs, and FGFs, and structural proteins such as syndecan and tenascin are expressed in transient, time and space-specific patterns in many organ rudiments, including the tooth [2].

References

  1. Artefactual gene induction during preparation of Xenopus laevis animal cap explants. Krain, B., Nordheim, A. Int. J. Dev. Biol. (1999) [Pubmed]
  2. Epithelial-mesenchymal signaling during tooth development. Thesleff, I., Vaahtokari, A., Kettunen, P., Aberg, T. Connect. Tissue Res. (1995) [Pubmed]
 
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