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Gene Review

gmhA  -  phosphoheptose isomerase

Escherichia coli UTI89

 
 
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Disease relevance of lpcA

  • Expression of the lpc genes individually behind the T7 promoter results in the production of each R. leguminosarum glycosyltransferase in E. coli membranes in a catalytically active form, demonstrating that lpcA, lpcB, and lpcC are structural genes [1].
 

High impact information on lpcA

  • A search for open reading frames (ORFs) and the analysis of possible codon usage in the intercistronic region indicate the absence of an additional gene (lpcA) between pepD and gpt [2].

References

  1. Cloning and overexpression of glycosyltransferases that generate the lipopolysaccharide core of Rhizobium leguminosarum. Kadrmas, J.L., Allaway, D., Studholme, R.E., Sullivan, J.T., Ronson, C.W., Poole, P.S., Raetz, C.R. J. Biol. Chem. (1998) [Pubmed]
  2. Accurate mapping of the Escherichia coli pepD gene by sequence analysis of its 5' flanking region. Henrich, B., Schroeder, U., Frank, R.W., Plapp, R. Mol. Gen. Genet. (1989) [Pubmed]
 
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